METFORMIN AS ADJUNCTIVE THERAPY IN COMBINATION WITH MULTIDRUG TREATMENT FOR MULTIBACILLARY LEPROSY: A PROTOCOL FOR A RANDOMIZED DOUBLE-BLIND, CONTROLLED PHASE 2 TRIAL IN INDONESIA (METLEP TRIAL) [VERSION 2; PEER REVIEW: 2 APPROVED]

Background The clinical management of leprosy is complicated by leprosy reactions (LR) causing irreversible nerve damage and disabilities.LR often require long-term use of corticosteroids causing serious side effects.Adjunct host-directed therapy (HDT) is a potentially attractive strategy in leprosy to prevent LR and associated immunopathology, mod

From the review of the theories of the cycle of violence, gender violence and the social construction of male and female identities, a non - experimental, exploratory and descriptive study was carried out with a nonrandom selection of students of a public university with the aim Pizza Peels to establish a balance and a prospective expectation of vi

My aim in this paper is to illuminate the question of how vicarious feeling is possible, by advancing our understanding of vicarious emotions.I address this problem by classifying the reactive attitude into two categories: the #leather-stockmans-breastplate. vicarious, and the self-reactive.I argue that guilt is constitutively tied to personal resp